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MCP live MCP 2025-11-25 streamable-http

io.github.sanjaysgk/can-immune

io.github.sanjaysgk/can-immune

Query CAN-IMMUNE: cancer neoantigen mutations, peptides, cell lines, MHC-I binding. Read-only.

Watch this dependency Share evidence report
Uptime
100.0%
5 direct probes · 30d
Response
2066ms
last probe
Tools
12
callable
Resources
0
readable
Prompts
0
available
Primary URL
https://canelib.erc.monash.edu/mcp
Score: 100/100
Handshake verified by our own probe.
pass Answers the MCP handshake 50/50
The handshake and the list calls succeeded on the primary URL.
pass Lists tools, resources or prompts 30/30
12 tools, 0 resources, 0 prompts returned.
pass 3 or more catalogue items 10/10
12 items in total; 3 or more earns these points.
pass Describes itself 10/10
94 characters; more than 30 earns these points.

Tools · 12

database_overview

Get the headline size of the CAN-IMMUNE database in one call. Returns total counts of mutations, genes, and unique mutant peptides, plus how many cell lines, tissues, and cancer types are cov…

search_genes

Find genes by symbol or full name, ranked by how mutated they are. Matches the gene symbol OR the full gene name (partial, case-insensitive) and returns each hit with its total mutation count…

get_gene

Get the full profile for one gene by exact symbol. Returns total mutations and how they split between cell lines vs tissues, unique mutant peptides, sample and transcript counts, UniProt acce…

search_cell_lines

Find cancer cell lines by name, ranked by mutation burden. Returns each matching cell line with its tissue of origin, cancer type, total mutations, unique mutant peptides, data sources (COSMI…

get_cell_line

Get the full profile for one cancer cell line by exact name. Returns tissue of origin, cancer type, total mutations, unique mutant peptides and genes, data sources, Cellosaurus and DepMap mod…

top_genes_in_cell_line

Rank the most-mutated genes within one specific cell line. Answers "what is the top mutated gene in <cell line>" / "which genes are most altered in <cell line>". Returns genes with their muta…

list_cancer_types

List cancer types (histology) ranked by mutation burden. Returns each cancer type / histology with its total mutations, unique samples, and unique genes, most-mutated first. Use to see which …

list_tissues

List primary tissues ranked by mutation burden. Returns each tissue (COSMIC primary-tissue samples only, kept separate from cell lines) with its total mutations, unique samples, and unique ge…

get_gene_mutations

List individual mutations in a gene (a bounded sample of rows). Each row gives the CAN-IMMUNE mutation ID (CANLIB...), the amino-acid change, the CDS change, mutation type (missense / complex…

get_mhc_binding

Look up a CACHED MHC-I binding prediction for a peptide + HLA allele. Returns the NetMHCpan result (best binding core, %Rank_EL, binder level SB/WB/NB, and neoepitope %Rank_Neo when computed)…

search

Search CAN-IMMUNE for genes and cell lines (ChatGPT connector interface). Returns {results: [{id, title, url}]} combining matching genes and cell lines, each with a stable `id` (like 'gene:TP…

fetch

Fetch the full record for an id returned by `search` (ChatGPT connector interface). Takes an id like 'gene:TP53' or 'cell_line:MDA-MB-231' and returns {id, title, text, url, metadata} where `…

How to use

Claude Desktop or claude.ai: add a custom connector (Customize → Connectors; on Team and Enterprise plans an owner adds it under Organization settings → Connectors) with this server URL: https://canelib.erc.monash.edu/mcp

Cursor or Cline: add to your MCP config:

{
  "mcpServers": {
    "io.github.sanjaysgk/can-immune": {
      "url": "https://canelib.erc.monash.edu/mcp",
      "transport": "streamable-http"
    }
  }
}