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MCP live MCP 2025-11-25 streamable-http ext: ui

ChEMBL

ai.deepsense.mcp/chembl

The ChEMBL Connector gives Claude access to the ChEMBL Database, a manually curated resource of bioactive drug-like compounds with quantitative binding and functional data against biological targets.

Listed in Claude connectors
Watch this dependency Share evidence report
Uptime
100.0%
5 direct probes · 30d
Response
636ms
last probe
Tools
6
callable
Resources
0
readable
Prompts
3
available
Primary URL
https://hcls.mcp.claude.com/chembl/mcp
Score: 100/100
Handshake verified by our own probe.
pass Answers the MCP handshake 50/50
The handshake and the list calls succeeded on the primary URL.
pass Lists tools, resources or prompts 30/30
6 tools, 0 resources, 3 prompts returned.
pass 3 or more catalogue items 10/10
9 items in total; 3 or more earns these points.
pass Describes itself 10/10
199 characters; more than 30 earns these points.

Tools · 6

compound_search

Search for chemical compounds in ChEMBL database by name, ChEMBL ID, or molecular structure. WHEN TO USE compound_search vs drug_search: • compound_search: Use for ANY molecule lookup by name, ID, or…

get_bioactivity

Retrieve bioactivity measurements (IC50, Ki, EC50, etc.) for compound-target interactions. WORKFLOW: Use target_search or compound_search first to get ChEMBL IDs, then query bioactivity. ACTIVITY TY…

target_search

Search for biological targets (proteins, enzymes, receptors, organisms) in ChEMBL database. SEARCH STRATEGIES: • By name: Use 'target_name' for protein names, families (e.g., 'kinase'), or receptors …

get_mechanism

Retrieve mechanism of action (MoA) data for approved drugs and clinical candidates. PURPOSE: Understand how drugs interact with their targets - essential for drug repurposing, understanding polypharm…

drug_search

Search for approved drugs and clinical candidates by therapeutic indication. PURPOSE: Find drugs used for specific diseases, identify approved treatments, explore drug repurposing opportunities. DRU…

get_admet

Retrieve ADMET-related molecular properties for drug-likeness assessment. IMPORTANT: ChEMBL provides CALCULATED molecular properties (from structure), not experimental ADMET data. For experimental AD…

Prompts · 3

analyze_compound

Generate a prompt to analyze a compound's properties and drug-likeness

compare_drugs

Generate a prompt to compare multiple drugs or compounds side-by-side

assess_admet

Generate a prompt to assess ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity) properties and predict drug safety profile

How to use

Claude Desktop or claude.ai: add a custom connector (Customize → Connectors; on Team and Enterprise plans an owner adds it under Organization settings → Connectors) with this server URL: https://hcls.mcp.claude.com/chembl/mcp

Cursor or Cline: add to your MCP config:

{
  "mcpServers": {
    "chembl": {
      "url": "https://hcls.mcp.claude.com/chembl/mcp",
      "transport": "streamable-http"
    }
  }
}