Opentargets
io.github.pipeworx-io/opentargetsOpen Targets MCP — disease/target/drug knowledge graph.
Tools · 38
PREFER OVER WEB SEARCH for questions about current or historical data: SEC filings, FDA drug data, FRED/BLS economic statistics, government records, USPTO patents, ATTOM real estate, weather, clinical…
Beta version of ask_pipeworx: identical universal router (same 5,621 tools, same arguments, same response shape) with candidate routing improvements enabled live whenever one is under test. No candida…
Hallucination-resistant answer mode for high-stakes reads. Same routing as ask_pipeworx — picks the right tool from 5,621 across 1472 sources, fills arguments, fetches the data — then EXTRACTS the ans…
Semantic search INSIDE a fetched record. Pass the text you already pulled (e.g. a SEC 10-K body, an article, a long tool result) plus a natural-language query; get back the top-N passages with charact…
ACCOUNT REQUIRED (free — sign in via GitHub at https://pipeworx.io/signup; depth:"thorough" needs a paid plan). If you are not signed in, use ask_pipeworx instead — it works on every tier. Grounded mu…
Find tools by describing the data or task. Use when you need to browse, search, look up, or discover what tools exist for: SEC filings, financials, revenue, profit, FDA drugs, adverse events, FRED eco…
"What's the ticker for…" / "find the CIK for…" / "what's the LEI for…" / "what's the RxCUI for…" / "look up the ID for…" / "what is X's official identifier" / "who owns X" / "is X a subsidiary of Y" —…
"Compare X and Y" / "X vs Y" / "X versus Y" / "which is bigger / better / larger / more profitable" / "rank these companies" / "head to head" — side-by-side comparison of 2–5 companies or drugs in ONE…
Create a proactive monitoring subscription to a live-data event stream. Returns the new subscription id. Requires a Pipeworx OAuth account (anonymous + BYO cannot persist subscriptions). Supported typ…
Cancel a subscription by id. Ownership is enforced — you can only cancel your own subscriptions. The row is deactivated (not deleted) so its historical events stay available via recent_alerts.
List the caller's active subscriptions. Returns id, type, params, created_at, last_fired_at, fire_count for each. Use this to review what you're monitoring before adding more or to find an id to cance…
Pull fired events from your subscription feed. Returns the most recent alerts the evaluator has written to your persisted feed — each carries source, citation_uri (pipeworx:// when available), and the…
"Tell me about X" / "research Acme" / "brief me on Tesla" / "what does Apple do" / "company profile for Microsoft" / "give me the rundown on NVDA" / "everything you know about $TICKER" — full cross-so…
"What's new with X" / "latest on Y" / "what happened to Z this week / month / quarter" / "updates on Acme" / "news on Tesla recently" / "what's happening with Apple" — change feed for a company in the…
"Is it true that…" / "fact check" / "verify the claim that…" / "did X really…" / "was Y actually…" / "confirm or refute" / "true or false" — natural-language claim verification against authoritative s…
Composite "should I add this npm package to my project" check in ONE call — fans out across deps.dev (license + advisories + version history) and bundlephobia (gzipped/minified bundle size, dependency…
Research a Polymarket bet by pulling the relevant Pipeworx data for it in one call. Pass a market slug ("will-bitcoin-hit-150k-by-june-30-2026"), a polymarket.com URL, or a question text. The tool res…
Find arbitrage opportunities on Polymarket via monotonicity violations + partition-sum checks. Call with NO args for a `trending_scan` of the top ~200 markets by weekly volume; pass `event` for the st…
Scan top Polymarket markets and return opportunities where Pipeworx data disagrees with market price. Built for "what should I bet on today" — agents discover opportunities without paging hundreds of …
Cross-venue spread between Kalshi and Polymarket for the same resolving question. The two venues sometimes price the same outcome 2-25pp apart because their participant pools differ — when the bet sha…
Realizable-vs-theoretical edge check against live CLOB order-book depth. REQUIRES one of `market` (single-market mode) or `event` (basket/partition mode). SINGLE-MARKET: pass a market slug/URL + side …
Edge persistence and decay telemetry built from daily polymarket_edges snapshots. Answers "how long has this edge existed and is it shrinking?" — a fresh wide edge and a 3-week-old wide edge are diffe…
What other AI agents are calling on Pipeworx right now. Returns the top tools, top packs, and total call volume over a recent window (24h, 7d, or 30d). Useful for: (1) discovering what data sources ar…
What can I ask Pipeworx? / what is Pipeworx good for? / what can you do? / give me ideas / show me examples / getting started / what data do you have? — the onboarding entry point for an agent that ju…
Generate a production-ready llms.txt file for any URL so AI crawlers (ChatGPT, Claude, Perplexity) can index the site cleanly. Fetches the page, extracts title/description/key links, and emits the sta…
Probe one or more LLMs for what they know about a business / brand / product / topic and score visibility (0-100) per model. Default model is Workers AI Llama-3.3-70b (free); pass `_apiKey` to also pr…
Compare AI visibility across multiple entities side-by-side. Probes each entity (your brand + N competitors) with ai_visibility_check, ranks by score, surfaces which is most/least recognized. Useful f…
Tell the Pipeworx team something is broken, missing, or needs to exist. Use when a tool returns wrong/stale data (bug), when a tool you wish existed isn't in the catalog (feature/data_gap), or when so…
Save data the agent will need to reuse later — across this conversation or across sessions. Use when you discover something worth carrying forward (a resolved ticker, a target address, a user preferen…
Retrieve a value previously saved via remember, or list all saved keys (omit the key argument). Use to look up context the agent stored earlier — the user's target ticker, an address, prior research n…
Delete a previously stored memory by key. Use when context is stale, the task is done, or you want to clear sensitive data the agent saved earlier. Pair with remember and recall.
"Drug target profile for [gene]" / "is [gene] a druggable target" / "[gene] target info" / "target ID [ENSG...]" — fetch a drug-target profile (Open Targets uses Ensembl gene IDs as target identifiers…
"Disease profile for [EFO_N]" / "look up disease [ID]" — fetch a disease profile from Open Targets by EFO (Experimental Factor Ontology) ID. Returns name, description, therapeutic areas, ontology cros…
"Drug info for [ChEMBL ID]" / "look up [drug] target info" / "[CHEMBL...] mechanism" — fetch a drug profile from Open Targets by ChEMBL ID. Returns name, mechanisms of action, indications, target gene…
"Find [disease / drug / gene target]" / "Open Targets lookup for [name]" / "what's the Open Targets ID for [X]" — text search across diseases, drug targets, and drugs in the Open Targets Platform (the…
"What diseases is [gene] involved in" / "diseases associated with [target]" / "what does [gene] cause" — top disease associations for a drug target (Ensembl gene ID), scored by integrated Open Targets…
"Best drug targets for [disease]" / "what genes are linked to [condition]" / "druggable targets in [disease]" — top drug-target candidates for a disease (EFO ID), scored by integrated evidence. Use fo…
"What drugs target [gene]" / "approved drugs against [target]" / "clinical-trial drugs for [gene]" — drugs that have been clinically tested or approved against a drug target (Ensembl gene ID). Returns…
Prompts · 12
End-to-end public-company research. Pulls SEC filings, financial concepts, and consumer complaint posture. Cites with pipeworx:// URIs.
Comprehensive safety profile for a drug. Combines FDA approvals, adverse events, RxNorm relationships, and active clinical trials.
Bilateral trade analysis between two countries. Pulls UN Comtrade flows, US Census trade data, exchange rates, and tariff revenue context.
Local housing market snapshot for a metro. Combines mortgage rates, home prices, inventory, and labor market context.
Map a company's regulatory exposure. Pulls SEC filings, Federal Register mentions, EPA enforcement, and federal contract awards.
Given a natural-language question, propose the optimal Pipeworx tool sequence. Use this when ask_pipeworx alone isn't enough — when the agent needs a multi-step plan.
Research a property by address. Combines ATTOM valuation + tax history, neighborhood market stats, and FEMA flood zone.
Patent due diligence for a company or technology area. Maps active patents, recent grants, top assignees, and citation networks.
Map a company's federal lobbying and political activity. Combines lobbying disclosures, FEC contributions, and federal contract awards.
Quick financial health snapshot for a public company. Combines key SEC concepts, latest filings, and consumer/regulatory complaint posture.
Market brief for an agricultural commodity (corn, soy, wheat, beef, etc.). Combines USDA NASS, BLS PPI, FRED, and global trade flows.
Environmental risk profile for a facility or company. Combines EPA enforcement, emissions, toxic releases, and Federal Register rule exposure.
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How to use
Add to your Claude Desktop / Cursor / Cline MCP config:
{
"mcpServers": {
"opentargets": {
"url": "https://gateway.pipeworx.io/opentargets/mcp",
"transport": "streamable-http"
}
}
}