Back to search
100
MCP live MCP 2026-07-28 http

chembl-mcp-server

io.github.cyanheads/chembl-mcp-server

Bioactivity and drug-discovery data over ChEMBL — compounds, protein targets, dose-response measurements, mechanisms of action, and clinical indications.

Watch this dependency

Get before/after evidence when observed tools, schemas, authentication access, availability or the endpoint changes.

Inspect evidence and set up a watch Share public evidence report
Uptime
100.0%
4 direct probes · 30d
Response
1446ms
last probe
Tools
7
callable
Resources
0
readable
Prompts
0
available
Primary URL
https://chembl.caseyjhand.com/mcp
Score: 100/100
Handshake verified by our own probe.
why this score
pass Answers the MCP handshake 50/50
The handshake and the list calls succeeded on the primary URL.
pass Lists tools, resources or prompts 30/30
7 tools, 0 resources, 0 prompts returned.
pass 3 or more catalogue items 10/10
7 items in total; 3 or more earns these points.
pass Describes itself 10/10
153 characters; more than 30 earns these points.

Tools · 7

chembl_search_molecules

Discovery entry point for compounds. Find by name / ChEMBL ID / InChIKey with the default search_type=name (supply query), or run a structure search with search_type exact | similarity | substructure …

chembl_get_bioactivities

The flagship compound↔target bioactivity bridge: measurements for a molecule (target deconvolution / selectivity), a target (lead finding), or both together (how potently one compound hits one target)…

chembl_search_targets

Resolve a protein/gene/UniProt accession to the ChEMBL target ID that chembl_get_bioactivities needs for the target→leads workflow. Supply at least one of accession (UniProt, e.g. P00533), gene_symbol…

chembl_get_drug_info

Pharmacology for a drug (molecule): mechanism(s) of action, the molecular target(s) it acts on, action type (inhibitor / agonist / …), first-approval year, and clinical indications with the max phase …

chembl_get_assay

Assay provenance behind a bioactivity row: description, type (binding / functional / ADMET / toxicity), the target it measures, organism, and ChEMBL's 1–9 confidence score (9 = direct assay on the pro…

chembl_dataframe_query

Run a read-only SQL SELECT over the bioactivity rows chembl_get_bioactivities staged on a canvas — rank, group, dedupe, and aggregate across the FULL set, not the inline preview. Reference each staged…

chembl_dataframe_describe

List the tables and columns staged on a canvas by chembl_get_bioactivities — inspect before calling chembl_dataframe_query to write correct SQL. Returns each table with its row count, kind (table | vi…

How to use

Add to your Claude Desktop / Cursor / Cline MCP config:

{
  "mcpServers": {
    "chembl-mcp-server": {
      "url": "https://chembl.caseyjhand.com/mcp",
      "transport": "http"
    }
  }
}